5JSW
tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-((((3a'R,6'R,6a'R)-2,2,2',2'-tetramethyldihydro-3a'H-spiro[[1,3]dioxolane-4,4'-furo[3,4-d][1,3]dioxol]-6'-yl)methyl)amino)-1H-imidazo[4,5-g]quinazolin-8(7H)-one
Summary for 5JSW
Entry DOI | 10.2210/pdb5jsw/pdb |
Related | 1P0D 4KWO 4LBU 4LEQ 4PUK 5I07 5JSV |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | co-crystallization, carbohydrates, transferase, transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 |
Total number of polymer chains | 1 |
Total formula weight | 44377.96 |
Authors | Ehrmann, F.R.,Nguyen, D.,Heine, A.,Klebe, G. (deposition date: 2016-05-09, release date: 2017-05-24, Last modification date: 2024-01-10) |
Primary citation | Ehrmann, F.R.,Schaefer, E.,Heine, A.,Diederich, F.,Klebe, G. Application of carbohydrates based lin-benzoguanines in a solvent-exposed subpocket of the tRNA-modifying Enzyme TGT To be Published, |
Experimental method | X-RAY DIFFRACTION (1.22 Å) |
Structure validation
Download full validation report