5JNU
Crystal structure of mouse Low-Molecular Weight Protein Tyrosine Phosphatase type A (LMPTP-A) complexed with phosphate
Summary for 5JNU
Entry DOI | 10.2210/pdb5jnu/pdb |
Related | 5JNR 5JNS 5JNT 5JNV 5JNW |
Descriptor | Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION (3 entities in total) |
Functional Keywords | protein tyrosine phosphatase, hydrolase, lmw-ptp, lmptp |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 36814.72 |
Authors | Stanford, S.M.,Aleshin, A.E.,Liddington, R.C.,Bankston, L.,Cadwell, G.,Bottini, N. (deposition date: 2016-04-30, release date: 2017-03-29, Last modification date: 2023-09-27) |
Primary citation | Stanford, S.M.,Aleshin, A.E.,Zhang, V.,Ardecky, R.J.,Hedrick, M.P.,Zou, J.,Ganji, S.R.,Bliss, M.R.,Yamamoto, F.,Bobkov, A.A.,Kiselar, J.,Liu, Y.,Cadwell, G.W.,Khare, S.,Yu, J.,Barquilla, A.,Chung, T.D.Y.,Mustelin, T.,Schenk, S.,Bankston, L.A.,Liddington, R.C.,Pinkerton, A.B.,Bottini, N. Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat. Chem. Biol., 13:624-632, 2017 Cited by PubMed: 28346406DOI: 10.1038/nchembio.2344 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.535 Å) |
Structure validation
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