5JNU
Crystal structure of mouse Low-Molecular Weight Protein Tyrosine Phosphatase type A (LMPTP-A) complexed with phosphate
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003993 | molecular_function | acid phosphatase activity |
A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0004726 | molecular_function | non-membrane spanning protein tyrosine phosphatase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
A | 0016791 | molecular_function | phosphatase activity |
A | 0017124 | molecular_function | SH3 domain binding |
A | 0042383 | cellular_component | sarcolemma |
B | 0003993 | molecular_function | acid phosphatase activity |
B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
B | 0004726 | molecular_function | non-membrane spanning protein tyrosine phosphatase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006470 | biological_process | protein dephosphorylation |
B | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
B | 0016791 | molecular_function | phosphatase activity |
B | 0017124 | molecular_function | SH3 domain binding |
B | 0042383 | cellular_component | sarcolemma |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue PO4 B 201 |
Chain | Residue |
B | CYS12 |
B | LEU13 |
B | GLY14 |
B | ASN15 |
B | ILE16 |
B | CYS17 |
B | ARG18 |
B | ASP129 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P11064 |
Chain | Residue | Details |
A | CYS12 | |
B | CYS12 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P11064 |
Chain | Residue | Details |
A | ARG18 | |
B | ARG18 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P11064 |
Chain | Residue | Details |
A | ASP129 | |
B | ASP129 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P11064 |
Chain | Residue | Details |
A | ALA1 | |
B | ALA1 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P24666 |
Chain | Residue | Details |
A | TYR131 | |
A | TYR132 | |
B | TYR131 | |
B | TYR132 |