5JCP

RhoGAP domain of ARAP3 in complex with RhoA in the transition state

5JCP の概要

• エントリーDOI: 10.2210/pdb5jcp/pdb
• 分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: rhoa, rhogap, arap3, signaling protein, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side: P61586
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 95406.20

構造登録者

Bao, H.,Li, F.,Wang, C.,Wang, N.,Jiang, Y.,Tang, Y.,Wu, J.,Shi, Y. (登録日: 2016-04-15, 公開日: 2016-06-22, 最終更新日: 2023-11-08)

• 主引用文献: Bao, H.,Li, F.,Wang, C.,Wang, N.,Jiang, Y.,Tang, Y.,Wu, J.,Shi, Y.; Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3; J.Biol.Chem., 291:16709-16719, 2016; PubMed: 27311713; DOI: 10.1074/jbc.M116.736140

実験手法

X-RAY DIFFRACTION (2.1 Å)