5JBC
Crystal structure of factor IXa variant V16I K98T Y177T I213V in complex with PPACK
Summary for 5JBC
Entry DOI | 10.2210/pdb5jbc/pdb |
Related PRD ID | PRD_000020 |
Descriptor | Coagulation factor IX, CALCIUM ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... (5 entities in total) |
Functional Keywords | crystal structure of factor ixa variant k98t in complex with egr-chloromethylketone, hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted : P00740 P00740 |
Total number of polymer chains | 2 |
Total formula weight | 32990.03 |
Authors | Kristensen, L.H.,Brandstetter, H. (deposition date: 2016-04-13, release date: 2016-06-01, Last modification date: 2024-01-10) |
Primary citation | Kristensen, L.H.,Olsen, O.H.,Blouse, G.E.,Brandstetter, H. Releasing the brakes in coagulation Factor IXa by co-operative maturation of the substrate-binding site. Biochem.J., 473:2395-2411, 2016 Cited by PubMed: 27208168DOI: 10.1042/BCJ20160336 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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