5JBB
Crystal structure of factor IXa variant V16I K98T Y177T I213V in complex with EGR-chloromethylketone
Summary for 5JBB
Entry DOI | 10.2210/pdb5jbb/pdb |
Related PRD ID | PRD_000288 |
Descriptor | Coagulation factor IX, CALCIUM ION, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, ... (6 entities in total) |
Functional Keywords | blood clotting, hydrolase, glycoprotein, haemostasis |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted : P00740 P00740 |
Total number of polymer chains | 2 |
Total formula weight | 33010.04 |
Authors | Kristensen, L.H.,Brandstetter, H. (deposition date: 2016-04-13, release date: 2016-06-01, Last modification date: 2024-01-10) |
Primary citation | Kristensen, L.H.,Olsen, O.H.,Blouse, G.E.,Brandstetter, H. Releasing the brakes in coagulation Factor IXa by co-operative maturation of the substrate-binding site. Biochem.J., 473:2395-2411, 2016 Cited by PubMed: 27208168DOI: 10.1042/BCJ20160336 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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