Summary for 5J94
Entry DOI | 10.2210/pdb5j94/pdb |
Descriptor | Cathepsin K, 2-{[(carbamoylsulfanyl)acetyl]amino}benzoic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | cysteine proteases, allosteric regulation, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Lysosome: P43235 |
Total number of polymer chains | 1 |
Total formula weight | 24889.87 |
Authors | Novinec, M.,Korenc, M.,Lenarcic, B.,Baici, A. (deposition date: 2016-04-08, release date: 2016-04-20, Last modification date: 2024-01-10) |
Primary citation | Novinec, M.,Korenc, M.,Caflisch, A.,Ranganathan, R.,Lenarcic, B.,Baici, A. A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods. Nat Commun, 5:3287-, 2014 Cited by PubMed: 24518821DOI: 10.1038/ncomms4287 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22002456664 Å) |
Structure validation
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