5J2U
Tubulin-MMAF complex
Summary for 5J2U
Entry DOI | 10.2210/pdb5j2u/pdb |
Related | 5IYZ |
Descriptor | Tubulin alpha-1B chain, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Tubulin beta-2B chain, ... (11 entities in total) |
Functional Keywords | cell cycle, cytoskeleton, tubulin fold, microtubule |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 8 |
Total formula weight | 265694.82 |
Authors | Waight, A.B.,Bargsten, K.,Doronina, S.,Steinmetz, M.O.,Sussman, D.,Prota, A.E. (deposition date: 2016-03-30, release date: 2016-08-17, Last modification date: 2024-01-10) |
Primary citation | Waight, A.B.,Bargsten, K.,Doronina, S.,Steinmetz, M.O.,Sussman, D.,Prota, A.E. Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics. Plos One, 11:e0160890-e0160890, 2016 Cited by PubMed: 27518442DOI: 10.1371/journal.pone.0160890 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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