5IS8

Crystal structure of mouse CARM1 in complex with inhibitor SA0271

Summary for 5IS8

• Entry DOI: 10.2210/pdb5is8/pdb
• Descriptor: Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl](2-chloroethyl)amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: protein arginine methyltransferase, catalytic domain, chromatin regulator, mrna processing, mrna splicing, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase
• Biological source: Mus musculus (Mouse)
• Cellular location: Nucleus: Q9WVG6
• Total number of polymer chains: 4
• Total formula weight: 174299.36

Authors

Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Hassenboehler, P.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J. (deposition date: 2016-03-15, release date: 2017-03-15, Last modification date: 2024-01-10)

• Primary citation: Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J.; Crystal structure of mouse CARM1 in complex with inhibitor SA0271; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.709 Å)