5IS8
Crystal structure of mouse CARM1 in complex with inhibitor SA0271
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, C | Histone-arginine methyltransferase CARM1 | polymer | 381 | 43109.8 | 4 | UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) In PDB | Mus musculus (Mouse) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | A, B, C | 5'-{[(3S)-3-amino-3-carboxypropyl](2-chloroethyl)amino}-5'-deoxyadenosine | non-polymer | 429.9 | 3 | Chemie (6D1) | |||
| 3 | A, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | D | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B, D, C: 130 - 507 (UniProt: Q9WVG6)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 172439.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1860.2 | |
| All* | Total formula weight | 174299.4 |
