5IR4

Crystal structure of wild-type bacterial lipoxygenase from Pseudomonas aeruginosa PA-LOX with space group C2221 at 1.48 A resolution

Summary for 5IR4

• Entry DOI: 10.2210/pdb5ir4/pdb
• Related: 5IR5
• Descriptor: Arachidonate 15-lipoxygenase, FE (II) ION, (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradec-5-enoyloxy)propyl (11Z)-octadec-11-enoate, ... (8 entities in total)
• Functional Keywords: non-heme iron enzyme, protein-phospholipid complex, oxidoreductase, eicosanoids, infectious diseases
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 1
• Total formula weight: 76607.81

Authors

Kalms, J.,Banthiya, S.,Galemou Yoga, E.,Kuhn, H.,Scheerer, P. (deposition date: 2016-03-12, release date: 2016-08-10, Last modification date: 2024-01-10)

• Primary citation: Banthiya, S.,Kalms, J.,Galemou Yoga, E.,Ivanov, I.,Carpena, X.,Hamberg, M.,Kuhn, H.,Scheerer, P.; Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa.; Biochim.Biophys.Acta, 1861:1681-1692, 2016; PubMed: 27500637; DOI: 10.1016/j.bbalip.2016.08.002

Experimental method

X-RAY DIFFRACTION (1.48 Å)