Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| A | 0034440 | biological_process | lipid oxidation |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue FE2 A 701 |
| Chain | Residue |
| A | HIS377 |
| A | HIS382 |
| A | HIS555 |
| A | ASN559 |
| A | ILE685 |
| A | HOH815 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue ZPE A 702 |
| Chain | Residue |
| A | THR109 |
| A | LEU182 |
| A | VAL185 |
| A | ASP190 |
| A | LEU193 |
| A | GLU373 |
| A | HIS382 |
| A | PHE415 |
| A | ILE416 |
| A | GLY419 |
| A | ALA420 |
| A | LEU424 |
| A | ASN607 |
| A | TYR609 |
| A | ILE685 |
| A | HOH871 |
| A | HOH897 |
| A | HOH1148 |
| A | SER22 |
| A | ILE23 |
| A | TRP105 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 703 |
| Chain | Residue |
| A | PHE24 |
| A | LEU28 |
| A | ALA33 |
| A | ARG37 |
| A | LEU100 |
| A | HOH825 |
| A | HOH857 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 704 |
| Chain | Residue |
| A | ARG67 |
| A | GLU514 |
| A | HOH1243 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 705 |
| Chain | Residue |
| A | THR339 |
| A | HIS340 |
| A | PRO341 |
| A | PRO579 |
| A | ALA580 |
| A | ASP582 |
| A | GLY643 |
| A | GLU647 |
| A | HOH943 |
| A | HOH1113 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 706 |
| Chain | Residue |
| A | PHE228 |
| A | ARG229 |
| A | GLN358 |
| A | LYS361 |
| A | THR362 |
| A | TRP592 |
| A | HOH921 |
| A | HOH990 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue GOL A 707 |
| Chain | Residue |
| A | GLN56 |
| A | ASP58 |
| A | ASN59 |
| A | LYS63 |
| A | LYS302 |
| A | ASP432 |
| A | PRO438 |
| A | ILE439 |
| A | GLN440 |
| A | CL710 |
| A | HOH811 |
| A | HOH855 |
| A | HOH900 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 708 |
| Chain | Residue |
| A | GLU99 |
| A | CYS389 |
| A | GLN393 |
| A | ALA407 |
| A | PHE410 |
| A | GLU411 |
| A | HOH843 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 709 |
| Chain | Residue |
| A | LYS87 |
| A | GLY88 |
| A | ALA444 |
| A | GLY447 |
| A | LEU451 |
| A | HOH1275 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 710 |
| Chain | Residue |
| A | LYS63 |
| A | LYS302 |
| A | LEU303 |
| A | GOL707 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 711 |
| Chain | Residue |
| A | GLU133 |
| A | GLU133 |
| A | HOH978 |
| A | HOH978 |
| A | HOH1251 |
| A | HOH1251 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 712 |
| Chain | Residue |
| A | GLN131 |
| A | ILE135 |
| A | ALA279 |
| A | ARG281 |
| A | ARG323 |
| A | HOH1066 |
Functional Information from PROSITE/UniProt
| site_id | PS00081 |
| Number of Residues | 11 |
| Details | LIPOXYGENASE_2 Lipoxygenases iron-binding region signature 2. SHPLhVLLaPH |
| Chain | Residue | Details |
| A | SER399-HIS409 | |
| site_id | PS00711 |
| Number of Residues | 15 |
| Details | LIPOXYGENASE_1 Lipoxygenases iron-binding region signature 1. HEmfvHlAQTHLVsE |
| Chain | Residue | Details |
| A | HIS372-GLU386 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU133 | |
| Chain | Residue | Details |
| A | HIS377 | |
| A | HIS382 | |
| A | HIS555 | |
| A | ASN559 | |
| A | ILE685 | |
