5IDZ

Structure of Human Enolase 2 in complex with (S)-(1-hydroxy-2-oxopiperidin-3-yl)phosphonate

Summary for 5IDZ

• Entry DOI: 10.2210/pdb5idz/pdb
• Related: 4ZA0 4ZCW
• Descriptor: Gamma-enolase, MAGNESIUM ION, [(3S)-1-hydroxy-2-oxopiperidin-3-yl]phosphonic acid, ... (5 entities in total)
• Functional Keywords: enolase gamma, glycolysis, neuron specific enolase, carbohydrate metabolism, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 97037.72

Authors

Leonard, P.G.,Muller, F.L. (deposition date: 2016-02-24, release date: 2017-02-22, Last modification date: 2023-09-27)

• Primary citation: Lin, Y.H.,Satani, N.,Hammoudi, N.,Felini, F.,Leonard, P.G.,Maxwell, D.,Link, T.,Lee, G.R.,Bosajou, A.,Duoli, S.,Marszalek, J.R.,Sun, Y.T.,McMurray, J.,Mandal, P.J.,DiFrancesco, M.E.,Czako, B.,Wang, A.,Bornmann, W.,DePinho, R.A.,Muller, F.L.; Pomhex, a cell-permeable Enolase inhibitor for Collateral Lethality targeting of ENO1-deleted Glioblastoma; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.63 Å)