5IDZ

Structure of Human Enolase 2 in complex with (S)-(1-hydroxy-2-oxopiperidin-3-yl)phosphonate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Gamma-enolase	polymer	440	48149.3	2	UniProt (P09104) Pfam (PF03952) Pfam (PF00113)	Homo sapiens (Human)	2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, Neuron-specific enolase, NSE
2	C, F (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	D, G (A, B)	[(3S)-1-hydroxy-2-oxopiperidin-3-yl]phosphonic acid	non-polymer		195.1	2	Chemie (6BM)
4	E, H (A, B)	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
5	I, J (A, B)	water	water		18.0	154	Chemie (HOH)

Sequence modifications

A, B: 1 - 434 (UniProt: P09104)

PDB	External Database	Details
His 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96298.5
Non-Polymers*	Number of molecules	6
	Total formula weight	739.2
All*	Total formula weight	97037.7

*Water molecules are not included.