5ICV

Crystal structure of human NatF (hNaa60) bound to a bisubstrate analogue

5ICV の概要

• エントリーDOI: 10.2210/pdb5icv/pdb
• 分子名称: N-alpha-acetyltransferase 60, MET-LYS-ALA-VAL-LIG, [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate, ... (4 entities in total)
• 機能のキーワード: transferase, acetylation, gnat, nat
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Golgi apparatus membrane : Q9H7X0
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 43618.96

構造登録者

Stove, S.I.,Magin, R.S.,Marmorstein, R.,Arnesen, T. (登録日: 2016-02-23, 公開日: 2016-06-22, 最終更新日: 2024-01-10)

• 主引用文献: Stve, S.I.,Magin, R.S.,Foyn, H.,Haug, B.E.,Marmorstein, R.,Arnesen, T.; Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.; Structure, 24:1044-1056, 2016; PubMed: 27320834; DOI: 10.1016/j.str.2016.04.020

実験手法

X-RAY DIFFRACTION (1.53 Å)