5IC4

Crystal structure of caspase-3 DEVE peptide complex

Summary for 5IC4

• Entry DOI: 10.2210/pdb5ic4/pdb
• Related: 5IC6
• Descriptor: Caspase-3 subunit p17, Caspase-3 subunit p12, DEVE peptide, ... (4 entities in total)
• Functional Keywords: apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 131396.68

Authors

Seaman, J.E.,Julien, O.,Lee, P.S.,Rettenmaier, T.J.,Thomsen, N.D.,Wells, J.A. (deposition date: 2016-02-22, release date: 2016-07-20, Last modification date: 2023-11-15)

• Primary citation: Seaman, J.E.,Julien, O.,Lee, P.S.,Rettenmaier, T.J.,Thomsen, N.D.,Wells, J.A.; Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues.; Cell Death Differ., 23:1717-1726, 2016; PubMed: 27367566; DOI: 10.1038/cdd.2016.62

Experimental method

X-RAY DIFFRACTION (2.65 Å)