5I9W
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with ANP
Summary for 5I9W
| Entry DOI | 10.2210/pdb5i9w/pdb |
| Descriptor | Ephrin type-A receptor 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 1,2-ETHANEDIOL, ... (4 entities in total) |
| Functional Keywords | transferase, tyrosine-protein kinase, receptor, atp-binding |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 35093.17 |
| Authors | Kudlinzki, D.,Linhard, V.L.,Gande, S.L.,Sreeramulu, S.,Saxena, K.,Heinzlmeir, S.,Medard, G.,Kuester, B.,Schwalbe, H. (deposition date: 2016-02-21, release date: 2016-11-09, Last modification date: 2024-01-10) |
| Primary citation | Heinzlmeir, S.,Kudlinzki, D.,Sreeramulu, S.,Klaeger, S.,Gande, S.L.,Linhard, V.,Wilhelm, M.,Qiao, H.,Helm, D.,Ruprecht, B.,Saxena, K.,Medard, G.,Schwalbe, H.,Kuster, B. Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs. ACS Chem. Biol., 11:3400-3411, 2016 Cited by PubMed: 27768280DOI: 10.1021/acschembio.6b00709 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.359 Å) |
Structure validation
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