5I35
Structure of the Human mitochondrial kinase COQ8A R611K with AMPPNP (Cerebellar Ataxia and Ubiquinone Deficiency Through Loss of Unorthodox Kinase Activity)
Summary for 5I35
Entry DOI | 10.2210/pdb5i35/pdb |
Descriptor | Atypical kinase ADCK3, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total) |
Functional Keywords | mitochondrial protein, kinase, ubiquinone biosynthesis, ubib clade kinase, structural genomics, psi-2, protein structure initiative, mitochondrial protein partnership, mpp, transferase, adck3, coenzyme q biosynthesis, adck3_human |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 46429.56 |
Authors | Bingman, C.A.,Stefely, J.A.,Pagliarini, D.J.,Mitochondrial Protein Partnership (MPP) (deposition date: 2016-02-09, release date: 2016-08-17, Last modification date: 2019-12-25) |
Primary citation | Stefely, J.A.,Licitra, F.,Laredj, L.,Reidenbach, A.G.,Kemmerer, Z.A.,Grangeray, A.,Jaeg-Ehret, T.,Minogue, C.E.,Ulbrich, A.,Hutchins, P.D.,Wilkerson, E.M.,Ruan, Z.,Aydin, D.,Hebert, A.S.,Guo, X.,Freiberger, E.C.,Reutenauer, L.,Jochem, A.,Chergova, M.,Johnson, I.E.,Lohman, D.C.,Rush, M.J.,Kwiecien, N.W.,Singh, P.K.,Schlagowski, A.I.,Floyd, B.J.,Forsman, U.,Sindelar, P.J.,Westphall, M.S.,Pierrel, F.,Zoll, J.,Dal Peraro, M.,Kannan, N.,Bingman, C.A.,Coon, J.J.,Isope, P.,Puccio, H.,Pagliarini, D.J. Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity. Mol.Cell, 63:608-620, 2016 Cited by PubMed: 27499294DOI: 10.1016/j.molcel.2016.06.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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