5I0B
Structure of PAK4
Summary for 5I0B
Entry DOI | 10.2210/pdb5i0b/pdb |
Descriptor | Serine/threonine-protein kinase PAK 4, 6-bromo-2-[1-methyl-3-(propan-2-yl)-1H-pyrazol-4-yl]-1H-imidazo[4,5-b]pyridine (2 entities in total) |
Functional Keywords | kinase, transferase-transferase inihibitor complex, transferase/transferase inihibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : O96013 |
Total number of polymer chains | 1 |
Total formula weight | 33745.03 |
Authors | Park, S.Y. (deposition date: 2016-02-03, release date: 2016-12-14, Last modification date: 2023-11-08) |
Primary citation | Park, J.K.,Kim, S.,Han, Y.J.,Kim, S.H.,Kang, N.S.,Lee, H.,Park, S.Y. The discovery and the structural basis of an imidazo[4,5-b]pyridine-based p21-activated kinase 4 inhibitor Bioorg. Med. Chem. Lett., 26:2580-2583, 2016 Cited by PubMed: 27117431DOI: 10.1016/j.bmcl.2016.04.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.09 Å) |
Structure validation
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