5I06
tRNA-guanine Transglycosylase (TGT) in co-crystallized complex with 6-Amino-4-[2-(4-methoxyphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Summary for 5I06
Entry DOI | 10.2210/pdb5i06/pdb |
Related | 1P0D 1Y5V 1Y5W 1Y5X 3EOS 3GE7 4FR6 4FSA 4KWO 4LEQ 4PUK 5I00 5I02 5I03 |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 6-AMINO-4-[2-(4-METHOXYPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ... (7 entities in total) |
Functional Keywords | co-crystallization, shigellosis, transferase, transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
Total number of polymer chains | 1 |
Total formula weight | 43815.00 |
Authors | Ehrmann, F.R.,Heine, A.,Klebe, G. (deposition date: 2016-02-03, release date: 2017-02-15, Last modification date: 2024-01-10) |
Primary citation | Ehrmann, F.R.,Stojko, J.,Heine, A.,Diederich, F.,Reuter, K.,Sanglier-Cianferani, S.,Klebe, G. Co-crystallization, Isothermal titration calorimetry and nanoESI-MS reveal dimer disturbing inhibitors To be Published, |
Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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