5HZH

Crystal structure of photoinhibitable Rac1 containing C450A mutant LOV2 domain

Summary for 5HZH

• Entry DOI: 10.2210/pdb5hzh/pdb
• Descriptor: Ras-related C3 botulinum toxin substrate 1,NPH1-1,Ras-related C3 botulinum toxin substrate 1, GUANOSINE-5'-TRIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... (6 entities in total)
• Functional Keywords: signaling protein, photoswitch, chimera
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63000
• Total number of polymer chains: 1
• Total formula weight: 38150.24

Authors

Tarnawski, M.,Dagliyan, O.,Chu, P.H.,Shirvanyants, D.,Dokholyan, N.V.,Hahn, K.M.,Schlichting, I. (deposition date: 2016-02-02, release date: 2016-12-21, Last modification date: 2024-01-10)

• Primary citation: Dagliyan, O.,Tarnawski, M.,Chu, P.H.,Shirvanyants, D.,Schlichting, I.,Dokholyan, N.V.,Hahn, K.M.; Engineering extrinsic disorder to control protein activity in living cells.; Science, 354:1441-1444, 2016; PubMed: 27980211; DOI: 10.1126/science.aah3404

Experimental method

X-RAY DIFFRACTION (2.6 Å)