5HUA

Structure of C. glabrata FKBP12-FK506 complex

Summary for 5HUA

• Entry DOI: 10.2210/pdb5hua/pdb
• Related: 5HT1
• Descriptor: FK506-binding protein 1, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total)
• Functional Keywords: fkbp12, fungal pathogen, fk506, self catalysis, isomerase
• Biological source: Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast)
• Cellular location: Cytoplasm : Q6FMA3
• Total number of polymer chains: 1
• Total formula weight: 13044.94

Authors

Schumacher, M.A. (deposition date: 2016-01-27, release date: 2016-09-14, Last modification date: 2024-03-06)

• Primary citation: Tonthat, N.K.,Juvvadi, P.R.,Zhang, H.,Lee, S.C.,Venters, R.,Spicer, L.,Steinbach, W.J.,Heitman, J.,Schumacher, M.A.; Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.; Mbio, 7:e00492-e00416, 2016; PubMed: 27118592; DOI: 10.1128/mBio.00492-16

Experimental method

X-RAY DIFFRACTION (1.3 Å)