5HUA

Structure of C. glabrata FKBP12-FK506 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
A	0003674	molecular_function	molecular_function
A	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
A	0005527	molecular_function	macrolide binding
A	0005575	cellular_component	cellular_component
A	0005737	cellular_component	cytoplasm
A	0006325	biological_process	chromatin organization
A	0006366	biological_process	transcription by RNA polymerase II
A	0006457	biological_process	protein folding
A	0016853	molecular_function	isomerase activity
A	0044183	molecular_function	protein folding chaperone
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0070651	biological_process	nonfunctional rRNA decay
A	1901710	biological_process	regulation of homoserine biosynthetic process
A	1901711	biological_process	negative regulation of homoserine biosynthetic process
A	1903332	biological_process	regulation of protein folding

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	binding site for residue FK5 A 201

Chain	Residue
A	TYR33
A	ALA88
A	TYR89
A	PHE94
A	PRO95
A	PHE106
A	HOH319
A	HOH350
A	HOH355
A	HOH369
A	HOH392
A	PHE43
A	HOH400
A	HOH404
A	ASP44
A	ARG49
A	PHE53
A	GLN61
A	VAL62
A	ILE63
A	TRP66

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Domain: {"description":"PPIase FKBP-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00277","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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