5HQN

Catalytic domain of murine Acid Sphingomyelinase (ASMase, ASM, SMPD1)

5HQN の概要

• エントリーDOI: 10.2210/pdb5hqn/pdb
• 関連するPDBエントリー: 5FI9 5FIB 5FIC
• 分子名称: Sphingomyelin phosphodiesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: smpd1, asm, asmase, sphingomyelinase, hydrolase-hydrolase inhibitor complex, hydrolase
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 110938.84

構造登録者

Gorelik, A.,Illes, K.,Heinz, L.X.,Superti-Furga, G.,Nagar, B. (登録日: 2016-01-21, 公開日: 2016-07-06, 最終更新日: 2020-07-29)

• 主引用文献: Gorelik, A.,Illes, K.,Heinz, L.X.,Superti-Furga, G.,Nagar, B.; Crystal structure of mammalian acid sphingomyelinase.; Nat Commun, 7:12196-12196, 2016; PubMed: 27435900; DOI: 10.1038/ncomms12196

実験手法

X-RAY DIFFRACTION (2.6 Å)