5FI9

Closed form of murine Acid Sphingomyelinase in complex with bisphosphonate inhibitor AbPA

Summary for 5FI9

• Entry DOI: 10.2210/pdb5fi9/pdb
• Related: 5FIB 5FIC 5HQN
• Descriptor: Sphingomyelin phosphodiesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: smpd1, asm, asmase, saposin, hydrolase
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 127282.57

Authors

Gorelik, A.,Illes, K.,Heinz, L.X.,Superti-Furga, G.,Nagar, B. (deposition date: 2015-12-22, release date: 2016-07-06, Last modification date: 2023-09-27)

• Primary citation: Gorelik, A.,Illes, K.,Heinz, L.X.,Superti-Furga, G.,Nagar, B.; Crystal structure of mammalian acid sphingomyelinase.; Nat Commun, 7:12196-12196, 2016; PubMed: 27435900; DOI: 10.1038/ncomms12196

Experimental method

X-RAY DIFFRACTION (2.543 Å)