5HQN
Catalytic domain of murine Acid Sphingomyelinase (ASMase, ASM, SMPD1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004767 | molecular_function | sphingomyelin phosphodiesterase activity |
| A | 0006685 | biological_process | sphingomyelin catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004767 | molecular_function | sphingomyelin phosphodiesterase activity |
| B | 0006685 | biological_process | sphingomyelin catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27435900","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FIB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FIC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HQN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"5FI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FIB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FIC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HQN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Cleavage; by CASP7","evidences":[{"source":"PubMed","id":"35705808","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P17405","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00415","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27435900","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FIB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HQN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00415","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27435900","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FIB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FIC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HQN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
