5HOC

p73 homo-tetramerization domain mutant II

Summary for 5HOC

• Entry DOI: 10.2210/pdb5hoc/pdb
• Related: 2KBY 2NB1 4A9Z 5HOB
• Descriptor: Tumor protein p73 (2 entities in total)
• Functional Keywords: transcription factor, tetramerization domain, p73, homo-tetramerization mutant, hetero-tetramerization, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : O15350
• Total number of polymer chains: 2
• Total formula weight: 12097.63

Authors

Coutandin, D.,Krojer, T.,Salah, E.,Mathea, S.,Sumyk, M.,Knapp, S.,Dotsch, V. (deposition date: 2016-01-19, release date: 2016-10-19, Last modification date: 2024-01-10)

• Primary citation: Gebel, J.,Luh, L.M.,Coutandin, D.,Osterburg, C.,Lohr, F.,Schafer, B.,Frombach, A.S.,Sumyk, M.,Buchner, L.,Krojer, T.,Salah, E.,Mathea, S.,Guntert, P.,Knapp, S.,Dotsch, V.; Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization.; Cell Death Differ., 23:1930-1940, 2016; PubMed: 27716744; DOI: 10.1038/cdd.2016.83

Experimental method

X-RAY DIFFRACTION (1.36007789334 Å)