5HNB

CDK8-CYCC IN COMPLEX WITH [6-Hydroxy-3-(3-methyl-benzyl)-1H-indazol-5-yl]-((S)-3-hydroxy-pyrrolidin-1-yl)-methanone

Summary for 5HNB

• Entry DOI: 10.2210/pdb5hnb/pdb
• Descriptor: Cyclin-dependent kinase 8, Cyclin-C, [6-hydroxy-3-(3-methylbenzyl)-1H-indazol-5-yl][(3S)-3-hydroxypyrrolidin-1-yl]methanone, ... (6 entities in total)
• Functional Keywords: cdk8 kinase / cyclin c, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P49336 P24863
• Total number of polymer chains: 2
• Total formula weight: 75525.85

Authors

Musil, D.,Blagg, J.,Schiemann, K. (deposition date: 2016-01-18, release date: 2016-04-27, Last modification date: 2024-01-10)

• Primary citation: Schiemann, K.; CDK8-CYCC IN COMPLEX WITH [6-Hydroxy-3-(3-methyl-benzyl)-1H-indazol-5-yl]-((S)-3-hydroxy-pyrrolidin-1-yl)-methanone; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.35 Å)