5HLK

Crystal structure of the ternary EcoRV-DNA-Lu complex with cleaved DNA substrate.

Replaces:  4ORJ

Summary for 5HLK

• Entry DOI: 10.2210/pdb5hlk/pdb
• Related: 5F8A
• Descriptor: Type-2 restriction enzyme EcoRV, DNA (5'-D(*AP*AP*AP*GP*AP*TP)-3'), DNA (5'-D(*AP*TP*CP*TP*TP*TP)-3'), ... (7 entities in total)
• Functional Keywords: hydrolase, protein-dna complex, lutetium, hydrolase-dna complex, hydrolase/dna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 6
• Total formula weight: 65575.56

Authors

Sangani, S.S.,Kehr, A.D.,Sinha, K.,Rule, G.S.,Jen-Jacobson, L. (deposition date: 2016-01-15, release date: 2016-11-09, Last modification date: 2023-09-27)

• Primary citation: Sinha, K.,Sangani, S.S.,Kehr, A.D.,Rule, G.S.,Jen-Jacobson, L.; Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex.; Biochemistry, 55:6115-6132, 2016; PubMed: 27786446; DOI: 10.1021/acs.biochem.6b00919

Experimental method