5HLD
E. coli PBP1b in complex with acyl-CENTA and moenomycin
Summary for 5HLD
Entry DOI | 10.2210/pdb5hld/pdb |
Related | 5HL9 5HLA 5HLB |
Descriptor | Penicillin-binding protein 1B, (2S)-5-methylidene-2-{(1R)-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, MOENOMYCIN, ... (4 entities in total) |
Functional Keywords | penicillin-binding protein, inhibitor complex, transpeptidase, transglycosylase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 85199.32 |
Authors | King, D.T.,Strynadka, N.C.J. (deposition date: 2016-01-14, release date: 2016-12-14, Last modification date: 2023-09-27) |
Primary citation | King, D.T.,Wasney, G.A.,Nosella, M.,Fong, A.,Strynadka, N.C. Escherichia coli Penicillin-Binding Protein 1B: Structural Insights into Inhibition. J. Biol. Chem., 2016 Cited by PubMed: 27899450DOI: 10.1074/jbc.M116.718403 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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