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5HLD

E. coli PBP1b in complex with acyl-CENTA and moenomycin

Functional Information from GO Data
ChainGOidnamespacecontents
A0008233molecular_functionpeptidase activity
A0008658molecular_functionpenicillin binding
A0008955molecular_functionpeptidoglycan glycosyltransferase activity
A0009252biological_processpeptidoglycan biosynthetic process
A0009274cellular_componentpeptidoglycan-based cell wall
A0046677biological_processresponse to antibiotic
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue 63V A 901
ChainResidue
ASER510
AHOH1062
AASP553
ASER572
AASN574
ATHR682
ATHR699
ATHR701
ATHR702
AASN703

site_idAC2
Number of Residues7
Detailsbinding site for residue M0E A 902
ChainResidue
AGLU233
AGLN271
ALYS274
AASN275
ATYR315
AGLU323
AHOH1080

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues23
DetailsTRANSMEM: Helical; Signal-anchor for type II membrane protein => ECO:0000305
ChainResidueDetails
AGLY64-LEU87

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: Proton donor; for transglycosylase activity => ECO:0000305|PubMed:10564478
ChainResidueDetails
AGLU233

site_idSWS_FT_FI3
Number of Residues1
DetailsACT_SITE: Acyl-ester intermediate; for transpeptidase activity => ECO:0000269|PubMed:10564478
ChainResidueDetails
ASER510

227344

PDB entries from 2024-11-13

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