5HHT

Crystal structure of E. coli transketolase triple variant Ser385Tyr/Asp469Thr/Arg520Gln

Summary for 5HHT

• Entry DOI: 10.2210/pdb5hht/pdb
• Descriptor: Transketolase 1, 1,2-ETHANEDIOL, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: thiamin diphosphate, transferase, engineered variant, pentose phosphate pathway
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 2
• Total formula weight: 149474.33

Authors

Dai, S.,Tittmann, K. (deposition date: 2016-01-11, release date: 2016-11-02, Last modification date: 2021-08-04)

• Primary citation: Affaticati, P.E.,Dai, S.B.,Payongsri, P.,Hailes, H.C.,Tittmann, K.,Dalby, P.A.; Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes.; Sci Rep, 6:35716-35716, 2016; PubMed: 27767080; DOI: 10.1038/srep35716

Experimental method

X-RAY DIFFRACTION (1.5 Å)