5HGV

Structure of an O-GlcNAc transferase point mutant, D554N in complex with peptide

Summary for 5HGV

Entry DOI	10.2210/pdb5hgv/pdb
Descriptor	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, TYR-PRO-GLY-GLY-SER-THR-PRO-VAL-SER-SER-ALA-ASN-MET-MET, URIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	point mutant, glycosyltransferase, ogt, transferase-peptide complex, transferase/peptide
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	165686.49
Authors	Janetzko, J.,Lazarus, M.B.,Walker, S. (deposition date: 2016-01-08, release date: 2016-09-14, Last modification date: 2023-09-27)
Primary citation	Janetzko, J.,Trauger, S.A.,Lazarus, M.B.,Walker, S. How the glycosyltransferase OGT catalyzes amide bond cleavage. Nat.Chem.Biol., 12:899-901, 2016 Cited by PubMed: 27618188 DOI: 10.1038/nchembio.2173 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation