5HGV
Structure of an O-GlcNAc transferase point mutant, D554N in complex with peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 719 | 80675.2 | 2 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (Human) | O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,OGT |
| 2 | B, D (B, D) | TYR-PRO-GLY-GLY-SER-THR-PRO-VAL-SER-SER-ALA-ASN-MET-MET | polymer | 14 | 1398.6 | 2 | UniProt (by SIFTS) (P68400) | Homo sapiens | |
| 3 | E, I (A, C) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 4 | F, H, K (A, B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | G, J (B, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 772 | Chemie (HOH) |
Sequence modifications
A, C: 313 - 1031 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Asn 554 | Asp 564 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164147.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1538.9 | |
| All* | Total formula weight | 165686.5 |
