5HGV
Structure of an O-GlcNAc transferase point mutant, D554N in complex with peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 719 | 80675.2 | 2 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (Human) | O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,OGT |
| 2 | B, D (B, D) | TYR-PRO-GLY-GLY-SER-THR-PRO-VAL-SER-SER-ALA-ASN-MET-MET | polymer | 14 | 1398.6 | 2 | UniProt (by SIFTS) (P68400) | Homo sapiens | |
| 3 | E, I (A, C) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) | |||
| 4 | F, H, K (A, B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | G, J (B, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 772 | Chemie (HOH) |
Sequence modifications
A, C: 313 - 1031 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Asn 554 | Asp 564 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164147.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1538.9 | |
| All* | Total formula weight | 165686.5 |
