5HFM
Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail
Summary for 5HFM
Entry DOI | 10.2210/pdb5hfm/pdb |
Related | 5HFL |
Descriptor | Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE (3 entities in total) |
Functional Keywords | hiv-1 fusion inhibitor, ile-asp-leu tail, hook-like tail, viral protein |
Biological source | Human immunodeficiency virus 1 (HIV-1) More |
Total number of polymer chains | 6 |
Total formula weight | 57007.50 |
Authors | |
Primary citation | Zhu, Y.,Su, S.,Qin, L.,Wang, Q.,Shi, L.,Ma, Z.,Tang, J.,Jiang, S.,Lu, L.,Ye, S.,Zhang, R. Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations Sci Rep, 6:31983-31983, 2016 Cited by PubMed: 27666394DOI: 10.1038/srep31983 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.298 Å) |
Structure validation
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