5HFF
The third PDZ domain from the synaptic protein PSD-95 (G330T, H372A double mutant) in complex with a mutant C-terminal peptide derived from CRIPT (T-2F)
Summary for 5HFF
Entry DOI | 10.2210/pdb5hff/pdb |
Related | 1BE9 5HDY 5HEB 5HED 5HET 5HEY 5HF1 5HF4 5HFB 5HFC 5HFD 5HFE |
Descriptor | Disks large homolog 4, Cysteine-rich PDZ-binding protein, GLYCEROL, ... (4 entities in total) |
Functional Keywords | pdz, glgf, dhr, adhesion, synapse, synaptic density, peptide-binding domain, peptide binding protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cell membrane; Peripheral membrane protein: P31016 Cytoplasm : Q792Q4 |
Total number of polymer chains | 2 |
Total formula weight | 14015.50 |
Authors | White, K.I.,Raman, A.S.,Ranganathan, R. (deposition date: 2016-01-06, release date: 2016-11-16, Last modification date: 2023-09-27) |
Primary citation | Raman, A.S.,White, K.I.,Ranganathan, R. Origins of Allostery and Evolvability in Proteins: A Case Study. Cell(Cambridge,Mass.), 166:468-480, 2016 Cited by PubMed: 27321669DOI: 10.1016/j.cell.2016.05.047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.749 Å) |
Structure validation
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