5HFF
The third PDZ domain from the synaptic protein PSD-95 (G330T, H372A double mutant) in complex with a mutant C-terminal peptide derived from CRIPT (T-2F)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Disks large homolog 4 | polymer | 119 | 12715.1 | 1 | UniProt (P31016) Pfam (PF00595) In PDB | Rattus norvegicus (Rat) | Postsynaptic density protein 95,PSD-95,Synapse-associated protein 90,SAP90 |
2 | B | Cysteine-rich PDZ-binding protein | polymer | 9 | 1116.3 | 1 | UniProt (Q792Q4) In PDB | Rattus norvegicus | Cysteine-rich interactor of PDZ three,Cysteine-rich interactor of PDZ3 |
3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A: 302 - 402 (UniProt: P31016)
B: 1 - 9 (UniProt: Q792Q4)
PDB | External Database | Details |
---|---|---|
Gly 297 | - | expression tag |
Ser 298 | - | expression tag |
Pro 299 | - | expression tag |
Glu 300 | - | expression tag |
Phe 301 | - | expression tag |
Thr 330 | Gly 330 | engineered mutation |
Ala 372 | His 372 | engineered mutation |
Asn 403 | - | expression tag |
Ser 404 | - | expression tag |
Arg 405 | - | expression tag |
Val 406 | - | expression tag |
Asp 407 | - | expression tag |
Ser 408 | - | expression tag |
Ser 409 | - | expression tag |
Gly 410 | - | expression tag |
Arg 411 | - | expression tag |
Ile 412 | - | expression tag |
Val 413 | - | expression tag |
Thr 414 | - | expression tag |
Asp 415 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Phe 7 | Thr 99 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13831.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 184.2 | |
All* | Total formula weight | 14015.5 |