Summary for 5HDB
Entry DOI | 10.2210/pdb5hdb/pdb |
Related PRD ID | PRD_002217 |
Descriptor | Integrin alpha-IIb, CALCIUM ION, MAGNESIUM ION, ... (15 entities in total) |
Functional Keywords | cell adhesion, platelet aggregation, membrane protein-immune system complex, integrin inhibitor, rgd mimetics, membrane protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 301439.38 |
Authors | Lin, F.Y. (deposition date: 2016-01-05, release date: 2016-02-03, Last modification date: 2020-07-29) |
Primary citation | Lin, F.Y.,Zhu, J.,Eng, E.T.,Hudson, N.E.,Springer, T.A. beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece. J.Biol.Chem., 291:4537-4546, 2016 Cited by PubMed: 26631735DOI: 10.1074/jbc.M115.705624 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7012 Å) |
Structure validation
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