5HCT
Endothiapepsin in complex with biacylhydrazone
Summary for 5HCT
Entry DOI | 10.2210/pdb5hct/pdb |
Related | 3PGI |
Descriptor | Endothiapepsin, DIMETHYL SULFOXIDE, GLYCEROL, ... (8 entities in total) |
Functional Keywords | hydrolase, inhibition |
Biological source | Cryphonectria parasitica (Chesnut blight fungus) |
Total number of polymer chains | 1 |
Total formula weight | 44483.03 |
Authors | |
Primary citation | Mondal, M.,Radeva, N.,Fanlo-Virgos, H.,Otto, S.,Klebe, G.,Hirsch, A.K. Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry. Angew.Chem.Int.Ed.Engl., 55:9422-9426, 2016 Cited by PubMed: 27400756DOI: 10.1002/anie.201603074 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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