5H8G

Crystal structure of CK2 with compound 7b

Summary for 5H8G

• Entry DOI: 10.2210/pdb5h8g/pdb
• Related: 5H8B 5H8E
• Descriptor: Casein kinase II subunit alpha, CHLORIDE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: kinase, inhibitor, ck2, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P68400
• Total number of polymer chains: 1
• Total formula weight: 41514.16

Authors

Ferguson, A.D. (deposition date: 2015-12-23, release date: 2016-02-10, Last modification date: 2023-09-27)

• Primary citation: Dowling, J.E.,Alimzhanov, M.,Bao, L.,Chuaqui, C.,Denz, C.R.,Jenkins, E.,Larsen, N.A.,Lyne, P.D.,Pontz, T.,Ye, Q.,Holdgate, G.A.,Snow, L.,O'Connell, N.,Ferguson, A.D.; Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo.; Acs Med.Chem.Lett., 7:300-305, 2016; PubMed: 26985319; DOI: 10.1021/acsmedchemlett.5b00452

Experimental method

X-RAY DIFFRACTION (2 Å)