5H8F
Structure of the apo human GluN1/GluN2A LBD
Summary for 5H8F
Entry DOI | 10.2210/pdb5h8f/pdb |
Related | 5H8H 5H8N 5H8Q 5H8R 5H8S |
Descriptor | Glutamate receptor ionotropic, NMDA 2A, Glutamate receptor ionotropic, NMDA 1, GLYCEROL, ... (6 entities in total) |
Functional Keywords | glun1, glun2a, nmda, receptor, transport protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : Q12879 Q05586 |
Total number of polymer chains | 2 |
Total formula weight | 66067.27 |
Authors | Wallweber, H.J.A.,Lupardus, P.J. (deposition date: 2015-12-23, release date: 2016-02-24, Last modification date: 2023-09-27) |
Primary citation | Hackos, D.H.,Lupardus, P.J.,Grand, T.,Chen, Y.,Wang, T.M.,Reynen, P.,Gustafson, A.,Wallweber, H.J.,Volgraf, M.,Sellers, B.D.,Schwarz, J.B.,Paoletti, P.,Sheng, M.,Zhou, Q.,Hanson, J.E. Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron, 89:983-999, 2016 Cited by PubMed: 26875626DOI: 10.1016/j.neuron.2016.01.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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