5H5K
ATP and CMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
Summary for 5H5K
Entry DOI | 10.2210/pdb5h5k/pdb |
Related | 2PBR 5H56 5H5B |
Descriptor | Thymidylate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | kinase, tranferase, complex, nucleotide binding, transferase |
Biological source | Aquifex aeolicus (strain VF5) |
Total number of polymer chains | 2 |
Total formula weight | 46701.49 |
Authors | Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2016-11-06, release date: 2017-06-28, Last modification date: 2023-11-08) |
Primary citation | Biswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K. Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate FEBS J., 284:2527-2544, 2017 Cited by PubMed: 28627020DOI: 10.1111/febs.14140 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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