5GTP
The agonist-free structure of human PPARgamma ligand binding domain in the presence of the SRC-1 coactivator peptide
Summary for 5GTP
Entry DOI | 10.2210/pdb5gtp/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1, MYRISTIC ACID, ... (5 entities in total) |
Functional Keywords | ppargamma, src-1, transcription |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 34506.00 |
Authors | Jang, J.Y.,Suh, S.W. (deposition date: 2016-08-23, release date: 2017-07-05, Last modification date: 2023-11-08) |
Primary citation | Jang, J.Y.,Koh, M.,Bae, H.,An, D.R.,Im, H.N.,Kim, H.S.,Yoon, J.Y.,Yoon, H.J.,Han, B.W.,Park, S.B.,Suh, S.W. Structural basis for differential activities of enantiomeric PPAR gamma agonists: Binding of S35 to the alternate site. Biochim. Biophys. Acta, 1865:674-681, 2017 Cited by PubMed: 28342850DOI: 10.1016/j.bbapap.2017.03.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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