5GRN

Crystal structure of PDGFRA in Complex with WQ-C-159

5GRN の概要

• エントリーDOI: 10.2210/pdb5grn/pdb
• 分子名称: Platelet-derived growth factor receptor alpha, N-[2-(dimethylamino)ethyl]-N-[[4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methyl]pyridine-3-carboxamide, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: pdgfra, wq-c-159, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane ; Single- pass type I membrane protein : P16234
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41281.78

構造登録者

Yan, X.E.,Yun, C.H. (登録日: 2016-08-11, 公開日: 2017-08-16, 最終更新日: 2023-11-08)

• 主引用文献: Yan, X.E.,Yun, C.H.; Crystal Structure of PDGFRA in Complex with WQ-C-159; To Be Published,

実験手法

X-RAY DIFFRACTION (1.77 Å)