5GM2
Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1
Summary for 5GM2
Entry DOI | 10.2210/pdb5gm2/pdb |
Related | 5GM1 |
Descriptor | O-methylransferase, S-ADENOSYL-L-HOMOCYSTEINE, (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one, ... (4 entities in total) |
Functional Keywords | tled, teleocidin, methyltransferases, terpene cyclization, transferase |
Biological source | Streptomyces blastmyceticus |
Total number of polymer chains | 18 |
Total formula weight | 605612.34 |
Authors | |
Primary citation | Yu, F.,Li, M.J.,Xu, C.Y.,Sun, B.,Zhou, H.,Wang, Z.J.,Xu, Q.,Xie, M.Y.,Zuo, G.,Huang, P.,Guo, H.,Wang, Q.S.,He, J.H. Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD Biochem.J., 473:4385-4397, 2016 Cited by PubMed: 27613858DOI: 10.1042/BCJ20160695 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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