5GM2
Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | O-methylransferase | polymer | 297 | 32823.1 | 18 | UniProt (A0A077K7L1) | Streptomyces blastmyceticus | Methyltransferase TleD |
| 2 | AA, AB, CA, EA, GA... (E, R, F, G, H...) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 18 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 3 | BA, BB, DA, FA, HA... (E, R, F, G, H...) | (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one | non-polymer | 437.6 | 18 | Chemie (TEX) | |||
| 4 | CB, DB, EB, FB, GB... (A, B, C, D, E...) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R: 1 - 289 (UniProt: A0A077K7L1)
| PDB | External Database | Details |
|---|---|---|
| Leu 290 | - | expression tag |
| Glu 291 | - | expression tag |
| His 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 590815.8 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 14796.5 | |
| All* | Total formula weight | 605612.3 |
