5GM2
Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | O-methylransferase | polymer | 297 | 32823.1 | 18 | UniProt (A0A077K7L1) Pfam (PF08241) | Streptomyces blastmyceticus | Methyltransferase TleD |
| 2 | AA, AB, CA, EA, GA... (E, R, F, G, H...) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 18 | Chemie (SAH) | |||
| 3 | BA, BB, DA, FA, HA... (E, R, F, G, H...) | (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one | non-polymer | 437.6 | 18 | Chemie (TEX) | |||
| 4 | CB, DB, EB, FB, GB... (A, B, C, D, E...) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R: 1 - 289 (UniProt: A0A077K7L1)
| PDB | External Database | Details |
|---|---|---|
| Leu 290 | - | expression tag |
| Glu 291 | - | expression tag |
| His 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 590815.8 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 14796.5 | |
| All* | Total formula weight | 605612.3 |
