5GM2

Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	O-methylransferase	polymer	297	32823.1	18	UniProt (A0A077K7L1) Pfam (PF08241) In PDB	Streptomyces blastmyceticus	Methyltransferase TleD
2	E, R, F, G, H...	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	18	Chemie (SAH)
3	E, R, F, G, H...	(2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one	non-polymer		437.6	18	Chemie (TEX)
4		water	water		18.0	166	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R: 1 - 289 (UniProt: A0A077K7L1)

PDB	External Database	Details
Leu 290	-	expression tag
Glu 291	-	expression tag
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	590815.8
Non-Polymers*	Number of molecules	36
	Total formula weight	14796.5
All*	Total formula weight	605612.3

*Water molecules are not included.