5GIC

Crystal structure of VDR in complex with DLAM-2P

Summary for 5GIC

Entry DOI	10.2210/pdb5gic/pdb
Related	5GID 5GIE
Descriptor	Vitamin D3 receptor, SRC1, (3~{R},5~{S})-5-[(2~{R})-2-[(1~{R},3~{a}~{S},4~{Z},7~{a}~{R})-7~{a}-methyl-4-[(2~{E})-2-[(3~{S},5~{R})-2-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-1-yl]propyl]-3-methyl-3-oxidanyl-1-(2-phenylethyl)pyrrolidin-2-one, ... (4 entities in total)
Functional Keywords	nuclear receptor, transcription
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	2
Total formula weight	30131.83
Authors	Shimizu, T.,Asano, L. (deposition date: 2016-06-23, release date: 2016-12-07, Last modification date: 2023-05-17)
Primary citation	Asano, L.,Waku, T.,Abe, R.,Kuwabara, N.,Ito, I.,Yanagisawa, J.,Nagasawa, K.,Shimizu, T. Regulation of the vitamin D receptor by vitamin D lactam derivatives. Febs Lett., 590:3270-3279, 2016 Cited by PubMed: 27500498 DOI: 10.1002/1873-3468.12348 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.352 Å)

Structure validation