5G4W

S. enterica HisA mutant D7N, D10G, Dup13-15 (VVR) with substrate ProFAR

Summary for 5G4W

• Entry DOI: 10.2210/pdb5g4w/pdb
• Related: 5G4E
• Descriptor: HISA, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL, ... (4 entities in total)
• Functional Keywords: isomerase, hisa, protein evolution, iad model, trpf
• Biological source: SALMONELLA ENTERICA
• Cellular location: Cytoplasm : V7IJE3
• Total number of polymer chains: 1
• Total formula weight: 28189.88

Authors

Guo, X.,Soderholm, A.,Newton, M.,Nasvall, J.,Duarte, F.,Andersson, D.,Patrick, W.,Selmer, M. (deposition date: 2016-05-17, release date: 2017-04-19, Last modification date: 2024-01-10)

• Primary citation: Newton, M.S.,Guo, X.,Soderholm, A.,Nasvall, J.,Lundstrom, P.,Andersson, D.I.,Selmer, M.,Patrick, W.M.; Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.; Proc. Natl. Acad. Sci. U.S.A., 114:4727-4732, 2017; PubMed: 28416687; DOI: 10.1073/pnas.1618552114

Experimental method

X-RAY DIFFRACTION (2.3 Å)