5G03
An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of Psammaplin C
Summary for 5G03
Entry DOI | 10.2210/pdb5g03/pdb |
Related | 5G01 5G0B 5G0C |
Descriptor | CARBONIC ANHYDRASE 2, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | lyase, natural product inhibitor, protein engineering, carbonic anhydrase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 29768.55 |
Authors | Mujumdar, P.,Supuran, C.T.,Peat, T.S.,Poulsen, S.A. (deposition date: 2016-03-16, release date: 2016-05-25, Last modification date: 2024-01-10) |
Primary citation | Mujumdar, P.,Teruya, K.,Tonissen, K.F.,Vullo, D.,Supuran, C.T.,Peat, T.S.,Poulsen, S. An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59:5462-, 2016 Cited by PubMed: 27172398DOI: 10.1021/ACS.JMEDCHEM.6B00443 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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