5FWQ

Apo structure of human Leukotriene A4 hydrolase

Summary for 5FWQ

Entry DOI	10.2210/pdb5fwq/pdb
Descriptor	HUMAN LEUKOTRIENE A4 HYDROLASE, ACETATE ION, ZINC ION, ... (6 entities in total)
Functional Keywords	hydrolase, leukotriene (lt) a4 hydrolase/aminopeptidase, lta4h
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	73186.66
Authors	Wittmann, S.K.,Kalinowsky, L.,Kramer, J.,Bloecher, R.,Steinhilber, D.,Pogoryelov, D.,Proschak, E.,Heering, J. (deposition date: 2016-02-19, release date: 2016-10-05, Last modification date: 2024-01-10)
Primary citation	Wittmann, S.K.,Kalinowsky, L.,Kramer, J.S.,Bloecher, R.,Knapp, S.,Steinhilber, D.,Pogoryelov, D.,Proschak, E.,Heering, J. Thermodynamic properties of leukotriene A4hydrolase inhibitors. Bioorg.Med.Chem., 24:5243-5248, 2016 Cited by PubMed: 27651294 DOI: 10.1016/j.bmc.2016.08.047 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.047 Å)

Structure validation